منابع مشابه
Neurodevelopment on Route p63
All known members of the p53 gene family, including the two homologs p73 and p63, have multiple biological functions. In neurons, p53 and p73 are known to regulate cell death in the developing and adult nervous system. A report by Jacobs et al. in this issue of Neuron shows that the more ancestral member of this gene family, p63, is an essential proapoptotic protein during neuronal development.
متن کاملNew Thinking on Neurodevelopment
Background: The main vector for transmission of malaria in India is the Anopheles culicifacies mosquito species, a naturally selected subgroup of which is completely refractory (R) to transmission of the malaria parasite, Plasmodium vivax; Results: Here, we report the molecular characterization of a serine protease (acsp30)-encoding gene from A. culicifacies, which was expressed in high abundan...
متن کاملSpotlight on p63 p63, Cellular Senescence and Tumor Development
Deficiency of p63, a p53-related protein, causes severe defects in epithelial morphogenesis. Studies of p63-compromised mouse models reveal that p63 deficiency induces cellular senescence both in cultured cells and in vivo, through regulation p19Arf/p53 and p16Ink4a/Rb pathways. An extensive tumor study of p63-compromised mice demonstrated that p63 deficiency does not predispose to, but rather ...
متن کاملFocus on astroglia and neurodevelopment
Radomska, K. 2014. Functional studies of the Quaking gene. Focus on astroglia and neurodevelopment. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Science and Technology 1152. 59 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-554-8960-1. The RNA-binding protein Quaking (QKI) plays a fundamental role in post-transcriptional gene regulation during mammalian...
متن کاملHuman Data on Bisphenol A and Neurodevelopment
December 2009 A 531 4.7% respectively, compared with the previous year. Also in 2007, China issued its first National Environment and Health Action Plan (2007-2015) (Ministry of Health of China 2007). The plan addresses the need to establish nationwide surveillance networks for environment and health, and for different government agencies and stake holders to share information and take responsi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Neuron
سال: 2005
ISSN: 0896-6273
DOI: 10.1016/j.neuron.2005.11.023